Antioxidant and Hypoglycemic Activity of Sacha Inchi Meal Protein Hydrolysate

Sacha inchi meal (SIM) is the residue from processing of oil crop sacha inchi. In present study, biological enzymolysis was performed on SIM protein to obtain hydrolysates, and then antioxidant hypoglycemic activities were evaluated. The results showed that scavenging rates alkaline protease hydrolysate (SAl) protamex (SPr) ABTS free radicals close vitamin C at 5 mg/mL, amounting 99.83 ± 0.33% 100.00 0.09%, respectively. dipeptidyl peptidase (DPP-IV) inhibitory SPr SAl also highest, concentration 2.5 their inhibition 74.15 0.68% 56.38 1.51%, respectively, with IC50 values 1.007 mg/mL 2.130 Moreover, compared model group, all hydrolysates increased glucose consumption by 187.01–348.79% (at 800 μg/mL) in insulin-resistant HepG2 cells, which better than positive drug Metformin. conclusion, have significant activity vitro; therefore, could be used as for functional food pharmaceutical development.